RUNX2 and neoplasm: By using TargetScan 5.1 and PicTar, we predicted putative genes of miR-34a which have not been experimentally identified yet, and finally obtained several putative targets which are correlated with tumor growth or metastasis, such as BCL6, CCNE2, CD97, CSNK1G3, CTNND1, DLL1, DKK1, GAS1, IGFBP3, LEF1, PGEA1, POFUT1, R-RAS, RUNX2, UHRF2, VCL, VEGFA, etc. (Table 1).