Examination of non-tumor bearing portions of the liver showed that hepatocytes around central veins in the H&E-stained sections of livers from mice inoculated with AAV-FGF19 were crowded, slightly smaller, and had increased cytoplasmic basophilia when compared with hepatocytes in the same area of livers from mice inoculated with AAV-FGF19-7 (Fig. 5A). The gene discussed is FGF19; the disease is neoplasm.