Mutations in ADAM23 have not been found in epileptic patients, but it interacts with LGI1, a gene associated with familial temporal lobe epilepsy-1 (ETL1) in human [44] and with LGI2, which is the causative gene for benign focal epilepsy in dogs [33]. The gene discussed is LGI1; the disease is autosomal dominant epilepsy with auditory features.