IL1B and Sjogren syndrome: A protein found in acinar cells of the lacrimal gland, AQP-5, was shown to be increased in the Sjogren type of dry eye syndrome, indicating possible leakage of such proteins into the tear film due to lymphocytic infiltration of the lacrimal gland.9 Solomon et al10 found an increase in inflammatory cytokines interleukin 1 (IL-1) alpha and IL-1 beta in both MGD and Sjogren syndrome, indicating increased protease activity on the ocular surface, mainly in the conjunctival epithelium.