Consumption of the HF diet for 3 weeks resulted in a significant decrease in hepatic CYP1A1, CYP1A2, and CYP2E1 mRNA levels to 10 ± 2%, 22 ± 2%, and 37 ± 7%, respectively, of the control values (Table 1). The gene discussed is CYP1A1; the disease is hydrops fetalis.