Although the effect of dermcidin in the increase of blood pressures lasted only for 4 h in the animal model, as the stress-induced protein, on mol/mol basis, was found to be 40 times more effective activator of cyclooxygenase when compared to that by ADP itself, dermcidin could be critically important in the development of CAD through thrombus in hypertension [12] even if the increase of plasma dermcidin level was only for a short time. Here, DCD is linked to hypertensive disorder.