Neither was detected at any significant level in patients with LGMD2A, while myogenin was detected in satellite cells in 0.7 ± 0.7% of the fibers in patients with LGMD2I, and 0.6 ± 0.3% in patients with BMD consistent with the higher level of recently regenerating fibers in these patients. The gene discussed is CAPN3; the disease is autosomal recessive limb-girdle muscular dystrophy type 2I.