The morphology and level of regeneration in patients with two null alleles in CAPN3 were compared with those in patients with limb girdle muscular dystrophy type 2I (LGMD2I) and patients with Becker muscular dystrophy (BMD), who clinically and morphologically resemble patients with LGMD2A [23]. This evidence concerns the gene CAPN3 and autosomal recessive limb-girdle muscular dystrophy type 2I.