Quantitative RT-PCR analysis showed a significant increase in expression of IL-6 (Figure 5A) and IL-11 (Figure 5B) mRNA expression in tumour xenografts in SP-treated animals compared to the control group (2.7±0.2 fold, P<0.01 and 2.6±0.1 fold, P<0.05 for SP vs control for IL-6 and IL-11, respectively). The gene discussed is IL6; the disease is neoplasm.