The effects of CF on leukocyte subsets in the lungs and BALF of OVA-treated mice, compared with the control group, included changes in the number of Gr-1+/CD11b+ granulocytes as well as CD3-/CCR3+ eosinophils; further, the decreases in CD3-/CCR3+ eosinophils were accompanied by concurrent decreases in eosinophils in the BALF (Figure 3C). Here, ITGAM is linked to cystic fibrosis.