Compared to TST SLC22A1 mRNA was in average 2,3-fold (± 1,4-fold) down-regulated in tumor tissue of most HCCs, whereas downregulation of SLC22A3 mRNA was lower (1,2-fold (± 1,2-fold)) (Figure 1C, D, E). This evidence concerns the gene SLC22A3 and neoplasm.