Low OCT1 (SLC22A1) mRNA expression levels were associated with advanced HCC stages as indicated by a higher frequency of T3 carcinomas (p = 0.025) with a larger tumor diameter (p = 0.035), a worse tissue differentiation as indicated by grading (p = 0.001) and higher AFP-levels (p = 0.019). The gene discussed is SLC22A1; the disease is hepatocellular carcinoma.