INS and diabetes mellitus: The number of patients receiving both monotherapy and combination use of diabetes drugs was as follows: sulfonylureas (n = 1,505, 45.4%), glinides (n = 341, 10.3%), α-glucosidase inhibitor (n = 685, 20.7%), biguanide (n = 550, 16.6%), thiazolidine (n = 287, 8.7%), and insulin (n = 284, 8.6%) (data not shown).