On the other hand, although 98% of astrocytomas were immunohistochemically positive for CAXII, higher CAXII expression levels were correlated with a higher histological grade and a poorer patient outcome either by univariate (P = 0.010) or multivariate (P = 0.039) survival analysis [9]. Here, CA12 is linked to astrocytoma (excluding glioblastoma).