Our findings herein support, albeit in a different way, the following conclusions: i) in the SCH and BPD ITC, similar reductions in neurons with small NeuN(+) nuclei, which most likely are interneurons, were present; and ii) lower densities of small NeuN(+) neurons appeared to be compensated for by insignificant increases in the densities of large NeuN(+) neurons, without concomitant reductions of total NeuN(+) neurons. Here, RBFOX3 is linked to spindle cell hemangioma.