These two loci, together with the other modest admixture signals on chromosome 12 and 1, and the absence of significant signals in locus-genome statistic elsewhere in the genome, suggest no evidence for a large genetic effect for type 2 diabetes that is racially/ethnically differentiated, such as that at the MYH9/ApoL1 locus for non-diabetic end stage renal disease [22], [39]. The gene discussed is APOL1; the disease is chronic kidney disease.