These results confirm previous findings from our group showing increased total TRPC3 channel expression on monocytes from patients with essential hypertension (3.21±0.59 for patients with hypertension, N = 20; vs. 1.36±0.07 for normotensive control subjects, N = 20; p<0.05; J Hypertens. The gene discussed is TRPC3; the disease is Hypertension.