Taken together, our analyses provide unequivocal evidence that BST1, CCDC62/HIP1R, DGKQ/GAK, GBA, ITGA8, LRRK2, MAPT, MCCC1/LAMP3, PARK16, SNCA, STK39, SYT11/RAB25 represent genuine PD risk loci, while the role of several other loci (e.g. ACMSD/TMEM163, and the HLA locus) remains to be determined. The gene discussed is GBA1; the disease is Parkinson disease.