In the present study, the combined treatment of EGFR siRNA and TKIs or antibody achieved increased tumor cell growth suppression (about 30% more at the most) (Figures 5, 6, 7, 8, and 9) in all the five NSCLC cell lines and increased apoptosis as high as by 100% (Figures 10 and 11). The gene discussed is EGFR; the disease is non-small cell lung carcinoma.