Serum MMP9 levels have also been shown to be significantly associated with breast cancer stage and size (Motovali-Bashi et al, 2010), gastric cancer stage (Dragutinovic et al, 2009), stromal reaction in gastric cancer (Shen et al, 2000), and CRC stage (Dragutinovic et al, 2011). This evidence concerns the gene MMP9 and gastric cancer.