Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) for D3–4/D1–2 mHLA-DR, D1–2 IL-6 concentration, and the combination of D3–4/D1–2 mHLA-DR and D1–2 IL-6 concentration, for the diagnosis of sepsis during the intensive care unit (ICU) stay. This evidence concerns the gene IL6 and Sepsis.