NINJ2 and ischemic stroke: Taken together, these led us to reason that clinical implications for the NINJ2 SNP, including a potential effect on the onset age of the first-ever ischemic stroke, need to be further elucidated 'within a carefully characterized stroke population' in a detailed manner that includes quantitative analyses of magnetic resonance (MR) images, by which many of diagnostic and therapeutic decisions are today guided in clinic.