Therefore, several institutions are making profound efforts to discover single-nucleotide variants for glaucoma by conducting a genome-wide association study (GWAS) [10]–[14], and there are a few published reports of the association of particular loci, such as the CAV1/CAV2 locus (7q31.1) [13] and the TMCO1 or CDKN2B-AS1 loci (1q24.1 or 9p21.3, respectively) [14], with POAG using Caucasian subjects. The gene discussed is CAV1; the disease is open-angle glaucoma.