Moreover, inhibition of Th17 cells with neutralising anti-IL-17 antibodies or with recombinant IL-25 prevents diabetes in NOD mice when treatment is started at 10 weeks but not 5 weeks of age [53], illustrating the importance of this cell population in the pathogenesis of T1D as well as the role of different time windows required for T1D preventive interventions. Here, IL17A is linked to diabetes mellitus.