In the present study, we found three novel splicing events, Sorbs1 exon 25 (exon 26 in human), Dclk1 exon 19, and Camk2d exon 14–16 (exon 14–15 in human), altered both in DM1 and in Mbnl1 knockout brains. The gene discussed is MBNL1; the disease is myotonic dystrophy type 1.