This increase was ∼30% in DM1 temporal cortex (Figure 3E), or apparently larger than that observed in the hippocampus of Mbnl1 knockout mice (Figure 2), although we could not conclude which of the following changes will have a stronger impact: (a) an increase from 0 to ∼2.5% in Mbnl1 knockout mice (Figure 2C), or (b) an increase from ∼10% to ∼30% in DM1 temporal cortex (Figure 3E). This evidence concerns the gene MBNL1 and myotonic dystrophy type 1.