Suzuki et al. showed that CpG-DNA encapsulated in cationic liposomes induces the expression of IL-12 and IFN-γ and that CpG-DNA-liposome co-encapsulated with ovalbumin (OVA) caused the induction of OVA-specific CTLs, which exhibited potent cytotoxicity against OVA-expressing tumor [21]. Here, IFNG is linked to neoplasm.