As shown in Figure 5A–D, the improved survival rate during the first week in CCR7−/− mice was accompanied by an attenuated increase in the expression of ANP, BNP, α-SKA, and β-MHC/α-MHC ratio CCR7−/− as compared with Wt mice following MI, potentially suggesting attenuated wall stress and improved myocardial function in CCR7 deficient mice. The gene discussed is NPPA; the disease is myocardial infarction.