However, the increase in myocardial expression of ANP, BNP and β-MHC/α-MHC ratio in CCR7−/− mice 6 weeks after MI, was accompanied by an increase in LV diameter and a decrease in posterior LV wall thickness in diastole in these mice as compared with Wt mice, indicating increased LV dilation in CCR7 deficient mice at this time-point (Table 3). Here, NPPA is linked to myocardial infarction.