Whereas Foxp3 expression was significantly decreased in post-MI HF as compared with sham operated Wt mice after 1 week, the myocardial expression of Foxp3 was markedly enhanced in CCR7−/− mice with no difference between sham operated and HF mice, potentially reflecting a phenotypic characteristic of these mice (Figure 6B). The gene discussed is FOXP3; the disease is hydrops fetalis.