Our group is currently investigating the unexplored potential of UA for the prevention and treatment of prostate cancer and has recently reported in two separate studies that UA can indeed suppress the growth of prostate xenograft in nude mice and also inhibit distant site metastasis by modulating the CXCR4/CXCL12 signaling cascade [18], [19]. The gene discussed is CXCR4; the disease is prostate carcinoma.