The median serum concentration of HSP-70 in our series of obese patients with NAFLD was clearly lower than that in controls, i.e., 0.13 (IQR = 0.1-0.54) ng/mL versus 1.09 (IQR = 0.81-2.33) ng/mL, p < 0.001, Figure 1. Here, HSPA1A is linked to metabolic dysfunction-associated steatotic liver disease.