IL6R and coronary artery disorder: The association of the IL6R rs7529229 variant with lowered risk of coronary heart disease provides robust evidence of a role for inflammation in pathogenesis of coronary heart disease that is consistent with previously reported findings based on the IL6R rs4537545 SNP (in LD with rs7529229, r2=1·00),32 although our analysis included more than twice the number of cases.