AKT1 and uveal melanoma: We also provide evidence that c-Met was a target of miR-34b/c, and miR-34b/c decreased endogenous c-Met, phosphorylated v-akt murine thymoma viral oncogene homolog (p-Akt), cyclin-dependent kinase (CDK) 4, and CDK6 protein levels in uveal melanoma cells.