In the first trimester, IL-2, IL-12, IFN-γ and IL-6 serum levels correlated with ECLAM score (IL-2 r = 0.524 P = 0.005, IL-12 r = 0.549 P = 0.007, IFN-γ r = 0.492 P = 0.017, IL-6 r = 0.515 P = 0.02) in SLE women. Here, IL6 is linked to systemic lupus erythematosus.