From these facts, we can conclude that PDGF-D-stimulated attainment of the EMT phenotype in PC3 cells is, partly, an outcome of suppression of miR-200 and that new strategies in which miR-200 would be up-regulated will become an auspicious approach for the treatment of invasive prostate cancer [69]. The gene discussed is PDGFD; the disease is Familial prostate cancer.