For instance, interluekin-1 (IL-1), interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10), nuclear factor-κB (NF-κB) and tumor necrosis factor-alpha (TNF-α) are among the major cytokines participating in regulation of immune system, angiogenesis, cell proliferation and tissue invasiveness during the formation of endometriosis [11-14]. The gene discussed is CXCL8; the disease is endometriosis.