Indeed, high levels of CXCL12 have been shown to be fugetactic to lymphocytes (Poznansky et al, 2000) and a B16 melanoma engineered to produce CXCL12 at high levels was found to be chemo-repellent to antigen-specific T cells (Vianello et al, 2006). The gene discussed is CXCL12; the disease is melanoma.