In addition, magnesium intake has been shown to decrease insulin levels (Ma et al, 1995; Fung et al, 2003; Song et al, 2004) and is associated with a lower risk of type 2 diabetes (Lopez-Ridaura et al, 2004; Song et al, 2004; Larsson and Wolk, 2007), a potential risk factor for colorectal cancer (Giovannucci et al, 2010). This evidence concerns the gene INS and type 2 diabetes mellitus.