HDAC9 and brain injury: This finding is corroborated by the work of Zhang et al. showing that the use of an HDAC inhibitor 4-dimethylamino-N-[5-(2-mercaptoacetylamino) pentyl] benzamide (DMA-PB) decreases microglial activation in a rat model of traumatic brain injury, and that this anti-inflammatory effect is associated with increased histone H3 acetylation [36].