The antibody-derived expression in the Human Protein Atlas project suggested either a tissue-specific expression or clinical usefulness in cancer diagnostics or therapy for the novel putative biomarkers BRD1, EZH2, FAM174B, GAD1, JAK3, JUP, MIXL1, SATB2 and ZNF473. Therefore, analysis of their in situ mRNA and protein expression in normal tissues could provide validation of antibody specificity. The gene discussed is FAM174B; the disease is cancer.