Hsp90β1 levels in the kidney of HFD-fed db/db mice was analyzed by immunoblotting and the results demonstrated similar hsp90β1 levels in the kidney homogenates and isolated mitochondria in animals treated with or without 17-DMAG (db/db-HF-S vs db/db-HF-G, Figure 4 A and B). The gene discussed is HSP90B1; the disease is hydrops fetalis.