The results observed under denervation conditions show that among the thirteen genes that displayed a significant correlation between transcriptional level expression and longevity during disease progression, five of them, Mef2c, Gsr, Col19a1, Calm1 and Snx10 may be considered potential biomarkers of longevity in ALS disease. This evidence concerns the gene COL19A1 and amyotrophic lateral sclerosis.