Indeed, extracts from the black chokeberry, Aronia melanocarpa[8] have been shown to have pronounced anticancer effects both in in vivo and in vitro studies on various colorectal cancer models [9], [10], [11], and leaves extracts of Aronia melanocarpa have been shown active on a non-solid tumor cell line, the p53-null promyeloblastic leukemia HL-60 cell line [30]. The gene discussed is TP53; the disease is colorectal cancer.