The Snail family includes Snail-1 (Snail), Snail-2 (Slug) and Snail-3 (Smuc), and has been shown to be over-expressed in a wide variety of human malignancies including oral [3], breast [4], hepatocellular [5], gastric [6], colon and skin carcinomas [7]. The gene discussed is SNAI1; the disease is skin carcinoma.