Interestingly, its expression can be induced directly by the transcription factor Twist, a key molecule for nasopharyngeal carcinoma (NPC) metastasis [136] and the expression of Twist can be induced by Latent membrane protein-1 (LMP1) encoded by Epstein-Barr virus (EBV) that is also involved in promoting NPC metastasis [137]. This evidence concerns the gene TWIST1 and nasopharyngeal carcinoma.