To determine whether increased glycolysis is also a shared feature of Shh-associated medulloblastomas and CGNPs, and whether this is, like lipogenesis, an E2F1-dependent event, we carried out immunofluorescence and western blot analysis of wild-type and E2F1-null mouse cerebella at postnatal day 7 (PN7), when CGNP proliferation is at its peak. Here, SHH is linked to medulloblastoma.