To verify the role of RelB in the radiosensitivity of PCa and the inverse relationship between IL-8 and PSA expressions in vivo, a stable RelB-expressing LNCaP clone was generated (Fig. 4A) and subcutaneously injected into the flanks of nude male mice; tumor growth was monitored for 50 days by measuring tumor size. This evidence concerns the gene KLK3 and posterior cortical atrophy.