We did not observe any association of KCNQ1 SNPs with diabetic complications, although there was a trend of the homozygous carriers of the risk C-allele of rs2237895 being more frequent among the diabetic patients with retinopathy compared to the patients without it (22.5 vs. 19.2%, p = 0.06, adjusted for age, sex, study and duration of type 2 diabetes). This evidence concerns the gene KCNQ1 and type 2 diabetes mellitus.