IFNA1 and osteosarcoma: The recently closed for accrual European and American Osteosarcoma Study Group (EURAMOS)-1 trial investigates whether maintenance treatment with interferon(IFN)-α-2b after standard chemotherapy for osteosarcoma patients who have a good response to preoperative chemotherapy (i.e., >90% necrotic tumor tissue) is effective [3, 4].