SCT has been reported to attenuate the progressive disease course of patients with polyneuropathy with organomegaly, endocrinopathy, M-protein and skin changes (POEMS) [5, 6], chronic inflammatory demyelinating polyneuropathy (CIDP) [7, 8], primary AL amyloidosis [9], and recently in a small series of patients with IgG MGUS- or MM-associated neuropathy [10], but it is unknown whether SCT may represent a rescue therapy for a wider range of patients with polyneuropathy and B cell dyscrasias and whether the possible beneficial effects outweigh risks associated with SCT. Here, MYOM2 is linked to chronic inflammatory demyelinating polyradiculoneuropathy.