We sought to investigate the dynamic responses of circulating proinflammatory cytokines (TNF-α and IL-6) and nitrosative stress (nitrotyrosine) induced by postchallenge hyperglycemia after 75 g oral glucose tolerance test (75 g-OGTT) and to evaluate their associations with the presence of CAD in patients without previous diagnosed T2DM. This evidence concerns the gene IL6 and coronary artery disorder.