Our study was consistent with some studies that revealed no impact of IDH mutations on the OS of AML cases although other studies suggested that IDH1 or IDH2 mutations conferred an adverse effect among AML with normal karyotype or AML with favorable genotype (NPM1 mutated/FLT3 wild type) [15,25-27,41]. The gene discussed is IDH1; the disease is acute myeloid leukemia.