IDH2 and acute promyelocytic leukemia: Interestingly, we observed that both IDH1 and IDH2 mutations were predominantly found in AML with maturation (AML-M2; n = 24/44) and acute promyelocytic leukemia (APL) (AML-M3; n = 11/44) which were different from AML-M1 as reported by others [5,27,30].