Genome-wide association studies (GWAS) of CRC have confirmed the hypothesis that part of the heritable risk for this disease is caused by common, low-risk variants and have identified various common variants associated with CRC risk [62], [63], [64], [65], [66] but none of the GWAS reported polymorphisms in the ABCB1 gene as major CRC risk factors. The gene discussed is ABCB1; the disease is colorectal carcinoma.