Although the causes of rheumatoid arthritis (RA), which is characterized by inflammation, pain, and swelling [11], are still not clear, the levels of proinflammatory cytokines (i.e., TNF-α, IL-1β) and inducible enzymes involved in inflammation (i.e., COX-2) are significantly increased at the inflammation sites. The gene discussed is PTGS2; the disease is rheumatoid arthritis.